What ceramides are
Ceramides are lipids. In the stratum corneum, the skin's outermost layer, they are the main lipid in the layered sheets between the cells, and that lipid domain is generally described as roughly equal molar parts of ceramides, cholesterol and free fatty acids.1 A review of skin barrier lipids calls this lipid matrix crucial to the barrier: it limits water loss through the skin and keeps substances from the environment from passing into the deeper layers.2
They are a family, not one substance. Each ceramide joins a sphingoid base to a fatty acid, and differences in chain length, hydroxylation and saturation make the family diverse1: one analysis of human stratum corneum identified 342 ceramide species, and a new class on top of the 10 generally known.3 Those findings describe the skin's own lipids. A ceramide in a cream is an ingredient a formulator chose, and its name says nothing about how much is present.
How to read the letters
Cosmetic ceramides are named after their two building blocks, and CosIng's descriptions show the pattern. The last letter names the base: P for phytosphingosine, S for sphingosine, G for sphinganine. The letters before it name the fatty acid part: N for a normal fatty acid, A for an alpha-hydroxy acid, and EO for an omega-hydroxy acid esterified with a second fatty acid.
| Label name | Base | Fatty acid part | Older INCI name |
|---|---|---|---|
| Ceramide NP | Phytosphingosine | Normal fatty acid | Ceramide 3 |
| Ceramide AP | Phytosphingosine | Alpha-hydroxy fatty acid | Ceramide 6 II |
| Ceramide EOP | Phytosphingosine | Omega-hydroxy acid esterified with a fatty acid | Ceramide 1 or Ceramide 1 A |
| Ceramide NS | Sphingosine | Normal fatty acid | Part of Ceramide 2 |
| Ceramide NG | Sphinganine | Normal fatty acid | Part of Ceramide 2 |
| Ceramide AS | Sphingosine | Alpha-hydroxy fatty acid | Ceramide 4 or Ceramide 5 |
| Ceramide EOS | Sphingosine | Esterified omega-hydroxy fatty acid | None recorded |
A name that starts with "Ceramide" and goes on is a different ingredient again. Ceramide NS Dilaurate, for example, is the diester of Ceramide NS and lauric acid.12
The old numbered names
Before the letters, cosmetic ceramides had numbers. CosIng's entry for Ceramide 3 records that the name was developed in 1997 and retired in 2014, and that trade names published under it are now also published under Ceramide NP.5 Two of the old names did not map one to one: Ceramide 2 covered both sphingosine-based and sphinganine-based ceramides and was split into Ceramide NS and Ceramide NG, while Ceramide 4 and Ceramide 5 both became Ceramide AS.8910
Retired does not mean gone from labels. The Personal Care Products Council, which sponsors the committee that assigns INCI names, says a retired name is kept in publication for a transition period13, and the EU glossary of label names that applies from 30 July 2026 still lists Ceramide 1, 1 A, 2, 3, 4, 5 and 6 II alongside the letter names.14 So Ceramide 1 on one pack and Ceramide EOP on another can describe the same kind of ingredient.
What they are listed for
CosIng lists Ceramide NP for hair conditioning and for skin conditioning - miscellaneous, which it defines as enhancing the appearance of dry or damaged skin by reducing flaking and restoring suppleness.415 Ceramide AP, Ceramide EOP, Ceramide AS and Ceramide EOS are listed for hair conditioning and skin conditioning, defined simply as maintaining the skin in good condition.67101115
The US Cosmetic Ingredient Review panel describes ceramides as working in cosmetics mainly as hair conditioning agents and miscellaneous skin conditioning agents. In 2020 it concluded that they are safe in the present practices of use and concentration described in its assessment.16 No ceramide name has an entry in the annexes of the EU cosmetics regulation.17 Function names describe a purpose in a formula, not a result on skin, and CosIng states that its information has no legal value.18
What to look for on the label
- Ceramide plus letters (NP, AP, EOP, NS, NG, AS, EOS) is a current INCI name; the table above decodes it.
- Ceramide plus a number is an older name for the same kind of ingredient, and still a valid EU label name.14
- A front-of-pack phrase such as "ceramide complex" is the brand's description. The list shows which ceramides are actually named.
- Position: below 1%, ingredients may be listed in any order22, so a ceramide's place says little about its amount. See ingredient list order.
- Check a whole list with the skincare ingredient checker to see what each name, old or new, is listed for.
A list can show which ceramides a product contains, not how much of each or how the formula performs. Nothing on this page is advice about treating a skin condition.
Sources
- Coderch L, López O, de la Maza A, Parra JL. Ceramides and skin function. American Journal of Clinical Dermatology 2003;4(2):107-29. pubmed.ncbi.nlm.nih.gov Checked 11 October 2026.
- van Smeden J, Bouwstra JA. Stratum corneum lipids: their role for the skin barrier function in healthy subjects and atopic dermatitis patients. Current Problems in Dermatology 2016;49:8-26. pubmed.ncbi.nlm.nih.gov Checked 11 October 2026.
- Masukawa Y, et al. Characterization of overall ceramide species in human stratum corneum. Journal of Lipid Research 2008;49(7):1466-76. pubmed.ncbi.nlm.nih.gov Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE NP: INCI name, description and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE 3 (retired INCI name): description, retirement and new name assignment. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE AP: INCI name, description, former name and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE EOP: INCI name, description, former names and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE NS: INCI name, description, former name and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE NG: INCI name, description, former name and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE AS: INCI name, description, former names and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE EOS: INCI name, description and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry CERAMIDE NS DILAURATE: INCI name and description. ec.europa.eu Checked 11 October 2026.
- Personal Care Products Council. INCI frequently asked questions (INCIpedia). incipedia.personalcarecouncil.org Checked 11 October 2026.
- Commission Implementing Decision (EU) 2025/1175 of 16 June 2025 on the glossary of common ingredient names for use in the labelling of cosmetic products. eur-lex.europa.eu Checked 10 October 2026.
- European Commission. CosIng: the functions of cosmetic ingredients and their definitions (83 functions), as the CosIng site serves them. ec.europa.eu Checked 11 October 2026.
- Burnett CL, et al. Safety assessment of ceramides as used in cosmetics. International Journal of Toxicology 2020;39(3 suppl):5S-25S. pubmed.ncbi.nlm.nih.gov Checked 11 October 2026.
- Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products, consolidated text of 18 May 2026. The article or annex entry relied on is named in each sentence citing it. Official Journal of the European Union. eur-lex.europa.eu Checked 11 October 2026.
- European Commission. CosIng, the cosmetic ingredient database: what it is and the limits of its information. single-market-economy.ec.europa.eu Checked 10 October 2026.
- European Commission. CosIng entry CHOLESTEROL: INCI name and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry PHYTOSPHINGOSINE: INCI name and functions. ec.europa.eu Checked 11 October 2026.
- European Commission. CosIng entry SPHINGANINE: INCI name and functions. ec.europa.eu Checked 11 October 2026.
- Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products, consolidated text of 1 May 2025, Articles 14, 19 and 33. Official Journal of the European Union. eur-lex.europa.eu Checked 10 October 2026.
Written for this site from the sources above and checked against them on 11 October 2026. Not reviewed by a dermatologist or toxicologist, and not medical advice. Spotted something wrong? Tell us.